CHE 426 Advanced Organic Chemistry

This course is designed to cover many of the topics discussed in Organic Chemistry I and II in more depth. Topics may include the general study of organic reaction mechanisms including Eyring plots, Hammond's postulate, Curtin-Hammett principle, isotope effects and acid-base catalysis; conformational control; stereoelectronics; Hückel molecular orbital theory; pericyclic reactions; aromaticity; free-radical species and reactions; nucleophilic substitutions; eliminations; additions; multi-step synthetic strategies; retrosynthetic strategies; and natural product synthesis. In addition, the student may be expected to develop literature research skills by preparing and presenting a project involving the total synthesis of a naturally occurring compound or a topic of current interest. Lecture only.

Credits

3

Prerequisite

CHE 234 and CHE 235L (both with a grade of "C" or better).

Distribution

(NS)

Offered

spring during even-numbered years.